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Log in now. The patient was on atenolol, rivaroxaban, alprazolam, and tianeptine for his current diseases. No other symptoms were accompanied.
Vital signs revealed a temporal temperature of Physical examination revealed multiple pinheaded vesicular lesions upon an erythematous base occupying an area on his right mammary region and back corresponding to T3—T5 dermatomes Fig. The area surrounding the vesicular eruption was flared and tender to touch. There was no history of psychological stress, immunodeficiency, malignancy, and immunosuppressive drug use in this patient. No previous history of similar lesions were reported, and patient was unaware of the occurrence of chickenpox in his childhood.
Based on the history and clinical presentation of the lesions, diagnosis of herpes zoster HZ was given. Treatment was started with valaciclovir 1 g thrice daily for 1 week, acyclovir cream, and paracetamol for pain. The patient was called on the 5th day from the beginning of the treatment to obtain information about the progress of the lesions and symptoms. He reported that the lesions started crusting, itching was added and the pain intensified. He was advised to continue with the current treatment and take codeine for pain management if necessary.
The patient provided written informed consent for publication of the research details and clinical images. Although SARS-CoV-2 primarily involves the respiratory, gastrointestinal, and neurological systems, it may also cause heterogeneous symptoms in different systems [ 6 , 7 ].
Skin involvement is also reported in several cases. HZ is characterized by inflammation of dorsal root ganglia or extra-medullary cranial nerve ganglia, associated with vesicular eruptions of the skin or oral mucous membrane in the area supplied by the affected nerve [ 12 ]. The incidence of HZ increases with age and reactivation of the virus is predisposed by trauma, and immunosuppressive therapy, and immunosenescence [ 13 ]. Walter et al. Also, Ruder et al. Although the exact reason remains unsolved, vaccine-induced immunomodulation caused by live attenuated vaccines and attenuated alloreactivity caused by inactivated vaccines may be responsible mechanisms for the reactivation of HZ [ 15 , 16 ].
Furthermore, HZ can precipitate during increased psychological stress, Lasserre et al. With increasing illness, exposure and mortality rates, restrictions and rules applied to prevent disease to spread, COVID 19 has been an effective source of stress not only in those who have had the disease, but also in the whole society.
Getting vaccinated against the disease may also have contributed to the stress factor, given all the discussions on social media and television. Although there is limited data to say that there is a definite relationship between covid vaccine and herpes reactivation, in order to examine possible relationships in this period when covid vaccination is aimed to reach large masses, epidemiological studies are needed to clarify the possible connection between vaccination and reactivation of herpesvirus infections.
No potential conflict of interest relevant to this article was reported. National Center for Biotechnology Information , U. Clin Exp Vaccine Res. Prior to the development of the varicella vaccine , chickenpox was a common childhood illness.
Most people were exposed to VZV in childhood and developed chickenpox in their younger years. In fact, doctors once encouraged families to expose their kids to chickenpox at an early age — after age 10 or so, the disease can be much more severe.
Adults who come down with chickenpox can experience serious and even life threatening complications like lung or brain infections. These days, children and adults can receive the varicella vaccine. This weaker version of the live virus causes the body to launch an immune response so that it recognizes — and fights off — VZV in the future. However, this is uncommon. One study found that the rate of shingles infection was 78 percent lower in vaccinated children than unvaccinated children.
The varicella vaccine became available in , so only time will tell its effects on the rates of shingles in older adults. The primary risk factor associated with getting shingles is a weakened immune system. Older age is associated with greater likelihood of health problems, including:.
Starting around age 50, your chance of getting shingles goes up. The severity of the disease and the risk of complications also increase with age. Shingles are no longer contagious after these blisters have crusted over. Typically, shingles shows up as a painful rash on an area of skin that is supplied by a single nerve.
This area, regardless of its location on the body, is known as a dermatome. Look for these hallmarks of a shingles rash:.
Some people also have other, more general symptoms, like :. To diagnose shingles, your doctor will ask you some questions about your symptoms. These may include:. Doctors can usually diagnose shingles by its distinctive rash and unique symptoms. In rare cases, though, if your doctor is uncertain whether you have shingles, you may undergo a diagnostic test. Testing is more common for people with greater risk factors for complications, including:.
To test for shingles, your doctor will use a swab to take a sample from a skin lesion. This will then be tested for VZV. A positive test indicates that you have shingles.
Your doctor may recommend certain medications to alleviate pain or treat infection. Valacyclovir and famciclovir are taken three times per day. All three have a 7-day course if you have an uncomplicated case of shingles.
Antiviral medications offer the most benefit for people over 50 and those who are immunocompromised, since these risk factors are associated with more persistent, severe shingles symptoms. Some people may need to take a longer course of antiviral medications or even be treated in the hospital with antivirals.
This is more likely if you have the following:. Some people experience shingles on the face.
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